Substantiation of protection of a neurovascular unit in the clinical model of cardiopulmonary bypass

This analytical review presents data on brain injury in surgical management of congenital heart disease. A brief description mechanisms and methods its prevention are given, moreover, a clinical case applying such techniques is given. The neurovascular unit vitro model advantages presented. protocol for modelling, the further application model, prospects using it studying intraoperative hypoxia systemic inflammatory response patient`s described.